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Tazarotene (Tazret forte cream 0.1% 15gm)
Tazret Forte cream 0.1% (Tazarotene) is used for the topical treatment of stable plaque psoriasis. The skin disease, psoriasis is marked by red, itchy, and scaly patches called plaques. Tazarotene is also indicated for the treatment of acne vulgaris. Acne is marked by inflamed or non-inflamed pimples on the skin.
Tazret Forte cream is manufactured by Gracewall and is available in the form of cream.
Mode of action of Tazret Forte cream:
Tazret cream contains the active ingredient Tazarotene, which is a synthetic, topical retinoid. The active substance induces the expression of a tumor suppressor gene called TIG3. In Psoriasis, Tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation.
Do not use Tazret Forte cream if:
You have hypersensitivity to Tazret forte cream or its components.
Always pre-inform your doctor in the following conditions:
You are a pregnant woman
You are a woman of reproductive potential
Dosage of the Tazret Forte cream 0.1%:
For the treatment of psoriasis, it is suggested that the treatment with Tazret forte cream with the dose increased to 0.1% if medically indicated and tolerated. Apply it once daily, in the evening to psoriatic lesions, use enough to cover the affected areas with a thin film with no more than 20% of body surface area. If a bath is taken before application, the skin should be patted dry before applying the medication. If moisturizers are used, they should be applied at least one hour before applying the cream. Avoid using it on the unaffected skin as these areas may be more susceptible to irritation.
For the treatment of acne, first clean the face gently. After the skin is dry, apply a thin film of cream once a day in the evening, to the area where acne lesions appear. Use enough amount to cover the affected area. Always wash your hand after application.
Method to apply the Tazret Forte cream:
Application of Tazret forte cream may cause excessive irritation in the skin of certain sensitive persons. In cases where it has been essential to temporarily the treatment, or the dosing has been reduced to a low concentration, or to time interval the patient can tolerate, treatment can be restarted, or the frequency of application can be increased as the patient becomes able to tolerate the treatment. The frequency of application should be closely monitored by careful observation of the skin tolerance and therapeutic response. It should be applied once daily.
If you forget or miss a dose of Tazarotene cream, do not try to make it up. Go back to your normal application schedule as soon as you can.
Call your doctor right away in case of an extra application of the cream.
Tazret Forte cream side effects:
Psoriasis: The most frequent side effects reported with Tazret cream 0.05% were limited to the skin. Those occurring in 15 to 30% of patients, included burning, stinging, pruritus, erythema, irritation, worsening of psoriasis, and skin pain. Side effects occurring in 5 to 10% of patients included rash, irritant contact dermatitis, fissuring, desquamation, dry skin, and skin inflammation.
Acne: The most frequent side effects reported with the drug in the treatment of acne occurring in 10 to 30% of patients, included stinging, burning, dry skin, desquamation, pruritus, and erythema. Events occurring in 1 to 10 % included fissuring, skin discoloration, localized edema, and skin pain.
The side effects that are mentioned above have been identified during the postmarketing of Tazret cream in clinical practice. Because they are observed voluntarily from a population of unknown size, it is not always possible to reliably evaluate their frequency or establish a cause relationship with the medication.
Interact with the Tazret Forte cream:
Concomitant dermatological cosmetics and medications that have a strong drying effect should be avoided. It is also advisable to rest a patient’s skin until the effects of such agents subside before use of Tazret forte cream.
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